The course provides a comprehensive overview of integrated material, structural, and vehicle testing under extreme environmental and load conditions. Using practical examples, it combines static, fatigue, and high strain rate testing with climatic, corrosion, vibration, road, altitude, and vacuum simulations. This goes from material and component level up to full system and vehicle validation (e.g. UGVs, UAVs, and space structures). Participants learn how standards-compliant test strategies according to MIL STD, RTCA DO 160, and ECSS reduce development risks and ensure operational readiness. The course is aimed at engineers working in R&D, testing, and reliability within aerospace, defense, and high demand industrial applications.